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Foundation for Biomedical Research of La Paz University Hospital
Foundation for Biomedical Research, University Clinical Hospital San Carlos
Foundation for Biomedical Research, University Clinical Hospital San Carlos. Cardiovascular Research Unit
Foundation for Biomedical Research, University Hospital 12 de Octubre
Foundation for Biomedical Research, University Hospital Ramón y Cajal
Foundation for Biomedical Research, University Hospital of Getafe
Foundation for Biomedical Research, University Hospital Puerta de Hierro
Complutense University of Madrid. School of Medicine. Department of Pharmacology

The mission of the Foundations for Biomedical Research of the different University Hospitals is to support, manage, coordinate and promote high quality multidisciplinary and translational basic, clinical and epidemiological as well as the teaching activities in all fields of Biomedical Sciences.

They coordinate the activities of the respective Health Research Institute.

The Foundations for Biomedical Research are conceived as a functional structure with the following functions/missions:

•  The development of multidisciplinary biomedical research of excellence,

•  The translational research in basic, clinical , technological , epidemiological and health services at the national and international level

•  The collaboration and cooperation between the different research groups and Institutions that Participate in the Institute

•  The development of cooperative programs with other Hospitals or Institutions

•  The access to official calls for public and/or private funding

•  The financial accountability and ongoing management of all research funds from grants and contracts, including the selection and recruitment of new researchers and the acquisition of new equipments/services .

•  The communication with funding agencies , acting as liaison on issues related to financial matters and during audits or monitoring visits

•  The presentation of all financial regulatory reporting requirements related to research projects

•  The elaboration of management reports to support the internal cost allocations , year-end reporting, future planning's and the selection of future research partners

•  The promotion and translation of the scientific results to the society , the National Health System, the scientific community , and the economic systems.

In summary, the mission of the Foundations for Biomedical Research is to manage and coordinate all of the resources for research (basic, clinical and epidemiological) and stimulate the development and innovation of the Hospital in order to contribute to the improvement, promotion and protection of the health of the population.

NIMGenetics. Biotechnological company of the Community of Madrid


 
Foundation for Biomedical Research of the University Hospital La Paz ( FIBHULP)

The Foundation manages the activity of the Institute for Health Research of the Hospiatl La Paz (IdiPAZ, www.idipaz.es). IdiPAZ was formally established on 15 December 2009) and coordinates the activity of several research groups from La Paz University Hospital (HULP), the Autonomous University of Madrid, the Madrid Health Service and the Pedro Lain Entralgo Agency for Training, Research and Health Studies in the Community of Madrid. One of the main areas of interest of IdiPAZ is Cardiovascular Research .
The mission of IdiPAZ is to establish itself as a leader in translational biomedical research on a national and international level. To achieve this, the Institute aims to promote high quality, basic, clinical, epidemiological and health services research. IdiPAZ manages all of the resources for research, development and innovation at the centre in order to contribute to the promotion and protection of the health of the population and facilitates access to official calls for public funding, both general and specific, for Health Research Institutes.
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PI: JL López Sendón MD, PhD. Chairman of the Department of Cardiology at La Paz University Hospital

Foundation for Biomedical Research of the University Clinical Hospital San Carlos ( FIBHCSC)

This Foundation manages the activity of the Institute for Health Research (IdISSC, http://www.idissc.org/) of the Clínico San Carlos University Hospital. The IdISSC is the structure that coordinates the R+D+i activity of the Hospital Clinico San Carlos with other entities such as the research groups of the Schools of Medicine, Pharmacy, Biological Sciences, Chemistry, Physics and Industrial Engineering of the Complutense University and the Polytechnic University of Madrid, the Pedro Laín Entralgo Agency and other entities belonging to the Madrid Health Service (SERMAS) as those of primary care providers in the area of influence of HCSC and some units of the Carlos III Hospital. Cardiovascular diseases is one of the five main areas of reserach of this Institution.
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PI: Julián Pérez Villacastín MD, PhD. Director of the Arrhythmias Unit of the Cardiovascular Research Institute at Clínico San Carlos University Hospital

Foundation for Biomedical Research of the University Hospital 12 de Octubre

The main objective of the Foundation for Biomedical Research of 12 de Octubre University Hospital is to promote research, training, and teaching in Biomedicine to improve the quality of care in the 12 de Octubre University Hospital. Furthermore, it is the entity that manages the Institute for Health Research of 12 de Octubre University Hospital (i+12) which also includes the following entities: Madrid Health Service (SERMAS), the Complutense University of Madrid, the Autonomous University of Madrid, and the Pedro Laín Entralgo Agency for Training, Research and Health Studies in the Region of Madrid.
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PI: Fernando Arribas Ynsaurriage MD, PhD. Chairman of the Cardiology Section at 12 de Octubre University Hospital

Foundation for Biomedical Research of the University Hospital Puerta de Hierro

The main objective of the Foundation for Biomedical Research of Puerta de Hierro University Hospital is to contribute researchers with a structure, support and resources needed to improve the quality of their results promoting economic development that would allow to increase scientific productivity with full transparency and a translational approach: from bench to bedside. The Foundation manages the scientific and technical activities of the Institute for Health Research of the University Hopsital Puerta de Hierro (IDIPHIM). The Institute englobes the following entities: the Research Foundation of the Hospital, the Madrid Health Service (SERMAS), the Autonomous University of Madrid, and the Pedro Laín Entralgo Agency for Training, Research and Health Studies in the Region of Madrid.
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PI: Jorge Toquero Ramos MD, PhD. Medical specialist of the Cardiology Department at Puerta de Hierro University Hospital

Foundation for Biomedical Research of the University Hospital Ramón y Cajal

The Foundation for Biomedical Research of Ramón y Cajal University Hospital was created to manage scientific and technical research and to enhance the areas of teaching in the field of health sciences at the Ramón y Cajal University Hospital. The Foundation manages the Institute for Health Research of Ramón y Cajal University Hospital (IRYCIS, http://www.irycis.org/composicion_fibio.htm) which integrates and coordinates several research groups from the Ramón y Cajal University Hospital, three Universities of Madrid (Complutense, Autonomous and Alcalá de Henares, the Madrid Health Service (SERMAS), the Carlos III Health Institute and the Pedro Lain Entralgo Agency for Training, Research and Health Studies in the Region of Madrid. The Institute was created as a multidisciplinary and translational biomedical research structure oriented to the basic, clinical, epidemiological, and health research services research encompassing assistance, research, and teaching both at national and international levels.

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PI: Antonio Hernández Madrid MD, PhD. Consultant Cardiologist of the Cardiology Department at Ramón y Cajal University Hospital and Concepción Moro is Professor of Cardiology in the School of Medicine of the Alcalá de Henares University .

Foundation for Biomedical Research of the Getafe University Hospital

The Foundation aims to promote scientific and technological research as well as training and teaching in health sciences, to improve the quality of care at the Getafe University Hospital. Its main specific objectives are the promotion and coordination of the development of scientific research programs applied to Biomedicine and Health Sciences as well as to facilitate research and training of researchers in collaboration with the Alfonso X El Sabio University, the Madrid Health Service (SERMAS), and with other public and private institutions. The activities of the Foundation are structured around three areas of basic and clinical research: 1) Fragility, aging and disability. 2 ) Inflammatory , infectious and chronic diseases. 3 ) Tumor pathology and systems. Within the area of chronic diseases, atrial fibrillation has been recognized as one of the main research activities for the Foundation.
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PI: Francisco García-Cosío Mir MD, PhD. Chairman of the Cardiology Department at Getafe University Hospital

Cardiovascular Research Unit of the University Clinical Hospital San Carlos

This unit is integrated in the Department of Cardiology of the San Carlos University Hospital. Threre are the main research lines in this Unit. First, the identification of biomarkers related to the prognosis, diagnosis and treatment of cardiovascular disease using different techniques of molecular biology and "omic"-based approaches, such as proteomics, genomics, and transcriptomics. Second, to identify the genetic alterations associated to sudden cardiac death in athletes and in patients with coronary heart disease. Third, the role of platelet adhesion and aggregation in the pathophysiology of acute and chronic coronary heart syndromes. The Unit has obtained in 2012 the ISO 9001 Quality Certification "for activities in the field of research, biobank and analytical techniques relating to genetic analysis processes, proteomic analysis , mass spectrometry, biochemistry and molecular biology".
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PI: Antonio López-Farré, PhD. Chairman of the Cardiovascular Research Unit at the University Clinical Hospital San Carlos

Complutense University of Madrid . School of Medicine . Department of Pharmacology

Research Lines:

The Department of Pharmacology included several research groups working on cardiovascular pharmacology

  • Cardiac pharmacology: Electrophysiological mechanisms involved in the genesis of cardiac arrhythmias, Endogenous and pharmacological regulation of cardiac ionic channels, Genetic basis of arrhythmia and drug-induced arrhythmia.
  • Vascular pharmacology. Signaling pathways involved in the generation and damage of target organs caused by systemic and pulmonar hypertension. Endogenous and pharmacological regulation of ionic channels in smooth muscle cells.
  • Pre-clinical evaluation of new cardiovascular drugs.

The Group of Cardiac Pharmacology use several techniques including the recording of cardiac action potential and ionic currents (patch-clamp technique) in isolated cardiomyocytes from animals, patients (in sinus rhythm or with chronic atrial fibrillation) and in heterologous expression systems. Molecular biology techniques (cell transfection, mutagenesis, western-blot, qPCR, immunocytochemistry, confocal microscopy), matematical and molecular modeling are also routinely used.

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PI: Juan Tamargo Menéndez, MD PhD. Professor of the Pharmacology at the Department of Pharmacology. School of Medicine . Complutense University.

NIMGenetics. Biotechnological company of the Community of Madrid

NIMGenetics is a biotechnological company of the Community of Madrid. It is a Genetic Diagnostics Centre authorized by the Community of Madrid's Health Department. NIMGenetics is specialized in the development and application of genomic high-resolution systems and will be mainly involved in the objective #2 of the Project: genotyping of the probands, and their direct relatives, diagnosed with arrhythmogenic syndromes.

NIMGenetics facilities are located in Faraday st, 7, Parque Científico de Madrid. Cantoblanco Campus , Madrid .
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